Shythdf2
Web(C) RT-qPCR analysis of MYC mRNA expression relative to GAPDH of mRNA from shYTHDF2 TNBC, HR+ and HER2+ breast cancer cell lines. (D) Cumulative distribution of … WebJan 11, 2024 · The lentiviral system was used to package YTHDF2 or shYTHDF2 lentiviral particles, and then virally infect the gastric cancer cell lines. The finally established …
Shythdf2
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WebJun 21, 2024 · Author summary Epstein–Barr virus (EBV) is a ubiquitous oncogenic virus that contributes to approximately 2% of all cancers by modulating a myriad of host cell activities. M6A is the most abundant RNA modification which is important for infection with HIV-1, HCV, Zika virus, KSHV and SV40 virus. The role of m6A modification and the … WebYTHDF2, also named as YTH domain-containing family protein 2, is a 579 amino acid protein, which contains 1 YTH domain. YTHDF2 specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a …
WebFigure 2 . YTHDF2 inhibited the activity of endometrial cell. (A,B) qRT-PCR and immunoblot analysis of YTHDF2 in endometrial cell HEC-1-A transfected with lentiviral shControl, YTHDF2 shRNA #1 or #2 as indicated for 72 h.(C,H) Cell proliferation measured by CCK8 assay of HEC-1-A cells stably expressing shYTHDF2 (C) or YTHDF2 (H) as indicated.The … WebOct 29, 2024 · The whole metastatic model was established and detected using an in vivo imaging system after injecting PC-3 shYTHDF2 and shNC cells into tail vein of nude mice. …
WebFeb 15, 2024 · 该研究揭示SUMO化修饰是m6A修饰阅读蛋白YTHDF2功能调控的一个新分子机制，并阐明了其在肿瘤发生中的重要作用。. RNA是遗传信息从DNA传递到蛋白质的关 … WebJan 8, 2024 · shYTHDF2#1-resistant YTHDF2 to the YTHDF2-depleted GSCs rescued the malignant phenotypes of GSCs (Fig. 2 d – h, Supple- mentary Fig. 2h-k), suggesting that …
Web100 of cultured RGC s treated by shYthdf2 (Fig ure 1C,D ; Figure 1 v figure supplement 1G,H ). In contrast, 101 the dendrite branching of RGCs with YTHDF1 KD using shYthdf1 was not significantly different from 102 control shRNA ( Figure 1 v figure supplement 1 I), while YTHDF3 KD using shYthdf3 caused a slight
WebFeb 1, 2024 · On one hand, as shown in Fig. S4, neither cell proliferation nor colony-formation was affected when YTHDF2 was either knockdown or knockout by either two … csi miami hurricane anthony castWebNov 18, 2024 · YTHDF2 inhibits IL-11 and Serpin E2 expression in HCC cells. (a) Volcano plots showing up (red) - or down (blue) -regulated genes in SMMC7721-shYTHDF2 versus … eagle dream company limitedhttp://www.jinpanmed.cn/archives/date/2024/04/14 csi miami in the windcsi miami look whoaposs taunting musicWebFeb 12, 2024 · Four stable H1299 cell lines (control, sh-YTHDF2, shYTHDF2-WT and shYTHDF2-K 571 R) were injected into the flanks of nude mice subcutaneously. Being … csi miami hurricane anthonyWebOct 12, 2024 · Messenger RNA m 6 A modification is shown to regulate local translation in axons. However, how the m 6 A codes in axonal mRNAs are read and decoded by the m 6 … csi miami money for nothing castWe analyzed The Cancer Genome Atlas (TCGA) and CHOICE datasets of Chinese patients with NSCLC to evaluate the expression profiles of m6A “write”, “eraser”, and “reader” genes (WERs) in LUAD23. The results showed that in both datasets, the mRNA expression levels of METTL3, VIRMA, RBM15, RBM15B, … See more Next, we investigated the effect of YTHDF2 on the aggressive capacities of LUAD in vitro. Our results showed that the ectopic overexpression of YTHDF2 in A549 … See more Given that YTHDF2 promotes mRNA degradation by targeting m6A-modified mRNAs to processing bodies in the cytoplasm, identifying the key factor that … See more eagle dreaming