Phosphopantetheine attachment site
WebJan 10, 2024 · To obtain active CAR enzyme, a phosphopantetheine group must be attached covalently to a conserved serine in the PCP domain mediated by a suitable … WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process / acyl binding / lipid binding / phosphopantetheine binding Processes fatty acid biosynthetic process / lipid A biosynthetic process / lipid biosynthetic process / response to drug Components cytoplasm / cytosol General Function
Phosphopantetheine attachment site
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WebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ... WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier … Hei Sook Sul, ... Li Chen, in Progress in Nucleic Acid Research and Molecular …
WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins ... which forms the 4′PPan cofactor attachment site. This α-helical region as well as two other α-helical segments (helix 1, residues 3–15 and helix 4, ... WebJul 17, 2024 · The PCP Ser702, which serves as the phosphopantetheine attachment site, is positioned 52 Å away from the bound AMP phosphate. By contrast, ...
WebPhylogenetic analysis of CARs. A) Domain organization of CAR sequences: adenylation domain (PFam PF00501), phosphopantetheine (PP) attachment site (PF00550), reductase domain (PF07793). B)... WebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Alternate IDs None Definition Binding an acyl group and presenting it for processing or …
Webthis effect was dependent upon an intact phosphopantetheine attachment site (PPAS) motif within the α/β hydrolase fold of NDRG1. Materials and Methods. Cell lines and culture. BeWo, JEG-3, CHO, and NIH3T3 lines were purchased from ATCC (Manassas, VA) and cultured as we previously detailed [38-41]. We also previously characterized and detailed the
Webreductase; KR, ketoreductase; PP, phosphopantetheine attachment site (acyl carrier pro-tein of PKSs and thiolation of NPSs); AMP, adenylation; CON, condensation; HGT, horizon-tal … early 品詞WebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are … early youth danwordWebDec 6, 2013 · For NRPS, the domains are: adenylation (A), condensation (C), oxidation (Ox), thioesterase (Te) and 4-phosphopantetheine attachment site (PP). Figure 3. Alignment of the PKS/NRPS cluster at genomic coordinates of 3092397–3133943 in D. solani D s0432-1 with the two closest homologs in D. zeae Ech586 and T. turnerae T7901. The improved ... early怎么读的WebPromotional Article Monitoring. Register your specific details and specific drugs of interest and we will match the information you provide to articles from our extensive database and email PDF copies to you promptly. csu stanislaus counseling programWebSep 29, 2024 · Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the … early zelda ii grinding locationshttp://amigo.geneontology.org/amigo/term/GO:0000036 early怎么读WebPhosphopantetheine attachment site Provide feedback. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. early怎么读英语发音