WebMar 15, 2024 · The transcription factor Grainyhead-like 3 ( GRHL3) plays an important role in the development and differentiation of normal urothelium. The contribution to UCB progression is still elusive. Differential expression of GRHL3 was assessed in normal human urothelium and in non-invasive and invasive bladder cancer cell lines.
Inhibition of retinoic acid signaling impairs cranial ... - ScienceDirect
WebInvasive urothelial carcinomas of the bladder (UCB) characteristically show a loss of differentiation markers. The transcription factor Grainyhead-like 3 (GRHL3) plays an important role in the development and differentiation of normal urothelium. The contribution to UCB progression is still elusive. Differential expression of GRHL3 was assessed in … WebGrainyhead-like 2 is a human homolog of Drosophila grainyhead. It inhibits epithelial-to-mesenchymal transition that is necessary for cell migration, and it is involved in neural … incline box conveyor
Grainyhead-like gene family - Wikipedia
The Grainyhead-like (Grhl) gene family is a group of highly conserved transcription factors, which work to regulate the expression of specific target genes. Grainyhead (Grh) was originally identified in Drosophila as being implicated within development through its role of regulating numerous genetic … See more Grainyhead-like genes are a family of highly conserved transcription factors that are functionally and structurally homologous across a large number of vertebrate and invertebrate species. For an estimated 100 million years or … See more Grhl1 Grhl1 is, much like the rest of the family of genes, involved in epithelial barrier formation and wound healing while the loss of Grhl1 is … See more Associated defects/diseases There are thousands of deaths a year of infants, either during or shortly after birth, and the leading … See more WebTwo rare variants reveal the significance of Grainyhead-like 3 Arginine 391 underlying non-syndromic cleft palate only Authors Wenbin Huang 1 2 , Qing He 3 , Mingzhao Li 1 2 , Yi … WebOct 18, 2016 · Using advanced imaging techniques and quantitative measurement, we show that genetic deletion of the highly-conserved transcription factor Grainyhead-like 3 … inbuilt function of string in python