WebMay 17, 2024 · Methods. Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to examine the expression profiles of circHECTD1, microRNA (miR)-137, and … WebFeb 9, 2024 · Knockdown of circHECTD1 inhibited proliferation and invasion in vitro, and also reduced the growth of tumor and prolonged the prognosis in vivo. Knockdown of …
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WebcircHECTD1 or PBX3 was expounded by dual-luciferase reporter, RNA immunoprecipitation (RIP) and RNA pull down assays. Results: We uncovered that circHECTD1 was ectopically up-regulated in GC tissues and cells. CircHECTD1 deciency sensitized DB-treatment in DB-evoked AGS and HGC-27 cells. In vivo assay, circHECTD1 silencing led to the tumor ... WebMar 14, 2024 · circHECTD1 is involved in SiO 2-induced HECTD1 downregulation. a In the SiO 2-induced EndMT, circHECTD1 may regulate the expression of its host gene, … tarrant county young lawyers association
CircHECTD1 up-regulates mucin 1 expression to accelerate …
WebMar 6, 2024 · Circular RNA HECTD1 (circHECTD1), for the first time, has been found to have roles in HS physiology. We determined the relative circHECTD1 levels in HS fibrous cells and tissues by RT-qPCR. Afterward, the effect of circHECTD1 knockdown on the proliferation, migration, invasion, fibrosis, and Transforming Growth Factor-beta/small … WebMay 17, 2024 · CircHECTD1 Lentivirus, miR-320-5p mimic, and SLC2A1 Lentivirus were transduced into cancer cells independently or together. circHECTD1, miR-320-5p, and SLC2A1 level were detected by qRT-PCR. WebSep 1, 2024 · The knockdown of circHECTD1 increased the apoptotic rates and the expressions of miR-136 and miR-320a, while its overexpression caused opposite effects in LPS-induced HBE and MLE-12 cells. Mechanistically, circHECTD1 bound to miR-320a and miR-136. miR-320a targeted PIK3CA and mediated the effect of circHECTD1 on … tarrant credit union fort worth